The COVID-19 pandemic has had a major impact on the way people live and work. Aside from illness, the pandemic has affected employee work arrangements, social lives, and psychological states. In March 2020, many non-essential employees at the University of Iowa began working remotely. UIHC and academic units varied in their approach to remote work, with many employees continuing to work on-site, while others worked—at least part time—remotely. To capture the magnitude of its effect and to offer potential solutions, we surveyed University of Iowa employees (faculty, staff, and postdocs) in May-June 2020 regarding their work arrangements, health, and well-being. Three additional follow-up surveys will examine changes in well-being over time (September 2020, November 2020, and February 2021).